Case Study, Cornell University and NUTRIFERON
While clinical studies are the gold standard for determining the effectiveness of a drug or a nutrient, it is sometimes difficult to avoid animal studies if you want to determine how that drug or nutrient works. And those basic "mechanism of action" studies are often a necessary prelude to the clinical studies.
That is why Shaklee's commitment not to use any animal studies in the testing of their products is so important.
If you are passionate about reducing the use of animals in research, you will be particularly impressed with Shaklee's latest research project.
Shaklee wanted to do some basic research on how Nutriferon works to prevent viral infections in the lung. So they contacted scientists at Cornell University to do those experiments.
Shaklee contacted those particular scientists to do the experiments because they were world experts in the field of immunology, and they were world experts in the development of model systems that can be used in the place of animal studies.
The scientists asked Shaklee if they would first support their research in developing an animal-free model system for determining how the airway epithelium (in layman's terms this refers to the layers of cells that line the lungs and windpipe) responds to viral infections.
Shaklee agreed to support the research at Cornell in developing a model of the human airway epithelium - even though that research itself did not involve any Shaklee products and was, therefore, of no direct benefit to Shaklee.
The Cornell scientists have published their first paper using this human airway epithelium (HAE) model system. (Palmero et al., Journal of Virology, 83: 6900-6908).
That particular paper showed how the lungs respond to a particular type of parainfluenza virus that is
responsible for croup and bronchitis in children.
Shaklee's support in the development of the HAE model system was acknowledged in that paper and will be acknowledged in all future papers using that model system.
Of course, the research didn't stop there. Shaklee also supported a research project by the same scientists to determine how Nutriferon helps the lungs resist infection by flu viruses.
I can't release all of the results of that study yet because the study has not yet been published. But I can tell you that the study showed that Nutriferon activates "natural killer cells" when a flu virus infects lung tissue.
This is a significant finding because, as their name suggests, natural killer cells play an important role in "killing" the flu virus. We already knew that Nutriferon helped fight viral infections, but we didn't know how. This research is an important part of the proof that Nutriferon is effective.
1) Shaklee has supported fundamental research at Cornell University into the development of a model system that allows scientists to test how human lung tissue responds to viral infections - and without the use of animals.
2) This study is significant in itself because it will allow scientists across the world to answer important scientific questions that cannot be addressed in clinical trials - and the lives of many thousands of laboratory animals will be spared in the process.
3) This is yet another example of Shaklee's commitment to supporting research that advances scientific knowledge - not just research that can be used in the marketing of their products. This commitment to true science is unique among food supplement companies.
4) These same scientist went on to use this model system to show that Nutriferon protects human lung tissue from viral infection by activating natural killer cells which destroy the virus.
5) This provides even stronger evidence of the effectiveness of Nutriferon by showing how it works.
To your health!
Dr. Stephen Chaney, Phd
Dr. Chaney has a BS in Chemistry from Duke University and a PhD in Biochemistry from UCLA. He currently holds the rank of Professor at a major university.
Dr. Chaney has taught biochemistry to medical and dental students for more than 30 years and has won several awards for teaching excellence.
He runs an active cancer research program and has published over 100 scientific articles and reviews in peer-reviewed scientific journals. He has also written two chapters on nutrition for a popular medical biochemistry textbook.